Trimethylsilyl Trifluoromethanesulfonate
Product Description
Trimethylsilyl Trifluoromethanesulfonate (TMSOTf) is a powerful silylating agent used in various chemical and industrial applications.
Product:
Trimethylsilyl Trifluoromethanesulfonate
CAS:
27607-77-8
Synonym:
TMS triflate; TMSOTf; Trifluoromethanesulfonic acid trimethylsilylester
Structure:
Typical Characteristics
Appearance
Colorless to faint yellow liquid
Boiling point
77 °C/80 mmHg
Density
1.228 g/cm3
Flash Point
40 °C
Melting point
<0 °C
Molecular Weight
222.26
Odor
Acrid odor
Purity
99%
Refractive index
1.36
Uses, Applications & Markets
Key applications
Markets
get a quote
We Offer Trimethylsilyl Trifluoromethanesulfonate
in various grades
A few of the grades available are listed below:
Trimethylsilyl Trifluoromethanesulfonate used in many
industry applications
Trimethylsilyl Trifluoromethanesulfonate (TMSOTf) is a powerful silylating agent used in various chemical and industrial applications. Here are some of its key uses:
- Silylation Reagent: TMSOTf is widely used as a silylation reagent in organic synthesis to introduce trimethylsilyl (TMS) groups into molecules, enhancing their stability and reactivity for further chemical reactions.
- Catalysis: It serves as a catalyst in various chemical reactions, including those in synthetic organic chemistry, where it helps to facilitate or accelerate reactions.
- Analytical Chemistry: TMSOTf is used in analytical chemistry to derivatize compounds for gas chromatography (GC) and mass spectrometry (MS), improving the detection and analysis of various analytes.
- Pharmaceutical Synthesis: It is employed in the synthesis of pharmaceutical compounds to modify and protect functional groups, enabling the creation of complex molecules with improved properties.
- Polymer Chemistry: TMSOTf is used in polymer chemistry to modify polymers and copolymers, enhancing their performance and properties for specific applications.
- Natural Product Synthesis: It is used in the synthesis of natural products and other complex organic molecules, aiding in the creation of intricate structures with high precision.
- Biochemical Research: TMSOTf is utilized in biochemical research to modify biomolecules, improving their stability and facilitating their study in various experimental conditions.
- Material Science: It is employed in material science for the modification and functionalization of materials, contributing to the development of advanced materials with specific properties.
- Chemical Manufacturing: TMSOTf is used in the manufacturing of chemicals and intermediates, where it plays a role in optimizing chemical processes and enhancing product quality.
- Environmental Chemistry: It is utilized in environmental chemistry for the analysis and modification of environmental samples, aiding in the study of pollutants and their behavior.