Trimethylsilyl Trifluoromethanesulfonate

CAS# 27607-77-8

Product Description

Trimethylsilyl Trifluoromethanesulfonate (TMSOTf) is a powerful silylating agent used in various chemical and industrial applications. 

Product:

Trimethylsilyl Trifluoromethanesulfonate

CAS:

27607-77-8

Synonym:

TMS triflate; TMSOTf; Trifluoromethanesulfonic acid trimethylsilylester

Structure:

Typical Characteristics

Appearance

Colorless to faint yellow liquid

Boiling point

77 °C/80 mmHg

Density

1.228 g/cm3

Flash Point

40 °C

Melting point

<0 °C

Molecular Weight

222.26

Odor

Acrid odor

Purity

99%

Refractive index

1.36

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We Offer Trimethylsilyl Trifluoromethanesulfonate
in various grades

A few of the grades available are listed below:

Trimethylsilyl Trifluoromethanesulfonate used in many
industry applications

Trimethylsilyl Trifluoromethanesulfonate (TMSOTf) is a powerful silylating agent used in various chemical and industrial applications. Here are some of its key uses:

  1. Silylation Reagent: TMSOTf is widely used as a silylation reagent in organic synthesis to introduce trimethylsilyl (TMS) groups into molecules, enhancing their stability and reactivity for further chemical reactions.
  2. Catalysis: It serves as a catalyst in various chemical reactions, including those in synthetic organic chemistry, where it helps to facilitate or accelerate reactions.
  3. Analytical Chemistry: TMSOTf is used in analytical chemistry to derivatize compounds for gas chromatography (GC) and mass spectrometry (MS), improving the detection and analysis of various analytes.
  4. Pharmaceutical Synthesis: It is employed in the synthesis of pharmaceutical compounds to modify and protect functional groups, enabling the creation of complex molecules with improved properties.
  5. Polymer Chemistry: TMSOTf is used in polymer chemistry to modify polymers and copolymers, enhancing their performance and properties for specific applications.
  6. Natural Product Synthesis: It is used in the synthesis of natural products and other complex organic molecules, aiding in the creation of intricate structures with high precision.
  7. Biochemical Research: TMSOTf is utilized in biochemical research to modify biomolecules, improving their stability and facilitating their study in various experimental conditions.
  8. Material Science: It is employed in material science for the modification and functionalization of materials, contributing to the development of advanced materials with specific properties.
  9. Chemical Manufacturing: TMSOTf is used in the manufacturing of chemicals and intermediates, where it plays a role in optimizing chemical processes and enhancing product quality.
  10. Environmental Chemistry: It is utilized in environmental chemistry for the analysis and modification of environmental samples, aiding in the study of pollutants and their behavior.