Trifluoroacetic Anhydride
Product Description
Trifluoroacetic anhydride (TFAA) is a versatile chemical reagent used in various industrial applications.
Product:
Trifluoroacetic Anhydride
CAS:
407-25-0
Synonym:
Perfluoroacetic anhydride; Trifluoroacetic acid anhydride
Structure:
Typical Characteristics
Appearance
Colorless liquid
Boiling point
39.5-40 °C
Density
1.511 g/cm3
Melting point
−65 °C
Molecular Weight
210.03
Odor
Pungent odor
Purity
≥99%
Refractive index
1.3
Uses, Applications & Markets
Key applications
Markets
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We Offer Trifluoroacetic Anhydride
in various grades
A few of the grades available are listed below:
Trifluoroacetic Anhydride used in many
industry applications
Trifluoroacetic anhydride (TFAA) is a versatile chemical reagent used in various industrial applications. Here are some of its key uses:
- Organic Synthesis: TFAA is commonly used as an acylating agent in organic synthesis, facilitating the introduction of trifluoroacetyl groups into organic molecules.
- Pharmaceutical Industry: It is utilized in the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs), particularly for introducing trifluoromethyl groups, which can enhance the biological activity and stability of drug molecules.
- Peptide Synthesis: TFAA is used in the protection and deprotection of amino groups during peptide synthesis, improving the efficiency and yield of peptide production.
- Analytical Chemistry: In analytical chemistry, TFAA is employed in the derivatization of compounds to enhance their detection and analysis by various techniques, such as gas chromatography (GC) and mass spectrometry (MS).
- Polymer Chemistry: TFAA is used in the modification of polymers, introducing trifluoroacetyl groups to improve their chemical resistance, thermal stability, and other desirable properties.
- Chemical Manufacturing: It serves as a reagent in the production of agrochemicals, dyes, and other fine chemicals, aiding in the synthesis of complex organic molecules.
- Materials Science: TFAA is utilized in the preparation of advanced materials, such as fluorinated polymers and coatings, which benefit from the unique properties imparted by the trifluoroacetyl group.
- Biotechnology: In biotechnology, TFAA is used for protein modification and labeling, facilitating the study of protein structure and function.
- Environmental Analysis: TFAA is employed in environmental analysis to derivatize and detect trace amounts of pollutants and contaminants, improving analytical sensitivity and accuracy.
- Laboratory Reagent: TFAA is a valuable reagent in research and development laboratories for developing new synthetic methodologies and exploring chemical reactions involving trifluoroacetylation.