Chloroquine

CAS# 54-05-7

Product Description

Chloroquine, a drug historically used primarily for the prevention and treatment of malaria, has found applications in various other medical and research areas due to its pharmacological properties.

Product:

Chloroquine

CAS:

54-05-7

Synonym:

Aralen; Chlorochin; 7-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline

Structure:

Typical Characteristics

Appearance

Colorless crystals

Density

1.050 g/cm3

Melting point

87 °C

Molecular Weight

319.87

Odor

Odorless

Purity

99%

Refractive index

1.6010

Uses, Applications & Markets

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We Offer Chloroquine
in various grades

A few of the grades available are listed below:

Chloroquine used in many
industry applications

Chloroquine, a drug historically used primarily for the prevention and treatment of malaria, has found applications in various other medical and research areas due to its pharmacological properties. Here's a look at some of its uses:

  1. Antimalarial: Chloroquine is most well-known for its role in preventing and treating malaria caused by Plasmodium parasites. It works by inhibiting the parasite's ability to break down and digest hemoglobin.
  2. Anti-inflammatory: Due to its mild immunosuppressive and anti-inflammatory effects, chloroquine is used in the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus.
  3. Antiviral Research: It has been explored as a potential antiviral agent against viruses like HIV, coronavirus, and influenza, though its effectiveness varies and is subject to ongoing research and clinical trials.
  4. Amoebiasis: Outside of malaria, chloroquine has been used to treat extraintestinal amoebiasis, an infection caused by amoebae spreading to organs outside the intestines, like the liver.
  5. Oncology Research: There is ongoing research into chloroquine's potential use in cancer therapy, particularly in its ability to inhibit autophagy, a process that cancer cells can exploit to survive under stress conditions.
  6. Photoprotection: Chloroquine has been used in treatment protocols for photodermatoses, offering protection against the harmful effects of sunlight in sensitive individuals.
  7. Research Tool: In scientific research, chloroquine is used to inhibit lysosomal autophagy in cultured cells, aiding in the study of cellular processes and disease mechanisms.