TRIS (Pharma grade)

CAS# 77-86-1

Product Description

TRIS (Pharma grade), also known as Tris(hydroxymethyl)aminomethane, is a highly pure buffer widely used in various industries, particularly in pharmaceuticals and biotechnology.

Product:

TRIS (Pharma grade)

CAS:

77-86-1

Synonym:

2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Tris base; Tris(hydroxymethyl)aminomethane; Trometamol

Structure:

Typical Characteristics

Appearance

White crystalline powder

Boiling point

219-220 °C/10 mmHg

Density

1.32 g/cm3

Melting point

167-172 °C

Molecular Weight

121.14

Odor

Slight odor

Purity

99.9%

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We Offer TRIS (Pharma grade)
in various grades

A few of the grades available are listed below:

TRIS (Pharma grade) used in many
industry applications

TRIS (Pharma grade), also known as Tris(hydroxymethyl)aminomethane, is a highly pure buffer widely used in various industries, particularly in pharmaceuticals and biotechnology. Here are some of its industrial uses:

  1. Pharmaceuticals: TRIS is used as a buffering agent in pharmaceutical formulations to maintain pH stability and enhance the efficacy of active ingredients in medications.
  2. Biotechnology: It is commonly used in biochemical and molecular biology laboratories as a buffer in solutions for DNA and RNA extraction, protein purification, and enzyme reactions.
  3. Medical Diagnostics: TRIS is employed in diagnostic kits and assays to stabilize reagents and ensure accurate and reliable results in various diagnostic tests.
  4. Cell Culture: In cell culture applications, TRIS buffers are used to maintain the desired pH levels in growth media, supporting optimal cell growth and viability.
  5. Protein Electrophoresis: It is used in buffer solutions for protein electrophoresis, aiding in the separation and analysis of proteins by maintaining a stable pH environment.
  6. Immunoassays: TRIS is used in immunoassay buffers to maintain pH stability and enhance the performance of antigen-antibody reactions in various immunological tests.
  7. Vaccine Production: In the production of vaccines, TRIS buffers are used to stabilize vaccine formulations and maintain the integrity of active components.
  8. Gene Therapy: It is used in gene therapy applications to prepare buffer solutions that are essential for the stability and delivery of genetic material.
  9. Chromatography: TRIS buffers are used in chromatography techniques to maintain pH and ionic strength, ensuring efficient separation and purification of biomolecules.
  10. Diagnostic Imaging: In diagnostic imaging, TRIS is used to prepare buffer solutions that enhance the stability and effectiveness of contrast agents.