Hydroxybenzotriazole

CAS# 80029-43-2

Product Description

Hydroxybenzotriazole (HOBt) is a versatile compound with several industrial applications. 

Product:

Hydroxybenzotriazole

CAS:

80029-43-2

Synonym:

1-Hydroxybenzotriazole hydrate

Structure:

Typical Characteristics

Appearance

White crystalline powder

Density

1.0 g/cm3

Melting point

155-158 °C

Molecular Weight

153.14

Purity

99%

Refractive index

1.488

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We Offer Hydroxybenzotriazole
in various grades

A few of the grades available are listed below:

Hydroxybenzotriazole used in many
industry applications

Hydroxybenzotriazole (HOBt) is a versatile compound with several industrial applications. Here are some of its uses:

  1. Peptide Synthesis: HOBt is widely employed as a peptide coupling reagent in the synthesis of peptides. It helps improve the efficiency of peptide bond formation and reduces side reactions, resulting in higher yields and purity of the desired peptides.
  2. Photographic Chemicals: In the field of photography, HOBt is used as a stabilizer and antioxidant in photographic developers and fixers. It helps prevent the degradation of photographic emulsions and enhances the shelf life of photographic chemicals.
  3. Corrosion Inhibitor: HOBt can serve as a corrosion inhibitor in metalworking fluids and lubricants. It helps protect metal surfaces from corrosion by forming a protective layer that inhibits the oxidation of metals exposed to corrosive environments.
  4. Pharmaceuticals: HOBt is utilized in the pharmaceutical industry as a key intermediate in the synthesis of various pharmaceutical compounds. It plays a crucial role in the preparation of drug candidates, pharmaceutical intermediates, and active pharmaceutical ingredients (APIs).
  5. Organic Synthesis: HOBt finds application as a versatile reagent in organic synthesis reactions, particularly in the formation of amide bonds, esterifications, and other carbon-carbon bond-forming reactions. It is valued for its ability to enhance reaction selectivity and efficiency.
  6. Antioxidant: Due to its antioxidant properties, HOBt is sometimes used as a stabilizer in polymer formulations, rubber products, and industrial coatings. It helps extend the service life of materials exposed to oxidative degradation.